NSCLC is the most common type of lung cancer and accounts for about 85%of lung cancers.4 NSCLC includes 3 main subtypes based on histology:
1. Adenocarcinoma: This type begins near the outside surface of the lung and grows slowly. It accounts for about 40% of lung cancers and occurs mainly in current or former smokers, but it is also the most common type of lung cancer seen in non-smokers, and more frequently seen in women and the young.4,5
2. Squamous cell carcinoma: This type generally begins in the lining of the airway in the larger breathing tubes, and often linked to a history of smoking. It accounts for about 25-30% of lung cancers and does not spread quickly.4,5
3. Large cell carcinoma: This type may occur in any part of the lung. It accounts for about 10-15% of lung cancers and tends to spread quickly.4,5
4. ACS. Non-Small Cell Lung Cancer. Available at: https://www.cancer.org/content/dam/CRC/PDF/Public/8703.00.pdf. https://www.cancer.org/content/dam/CRC/PDF/Public/8705.00.pdf. https://www.cancer.org/content/dam/CRC/PDF/Public/8706.00.pdf. Accessed: 2 May 2019.
5. ICS. Understanding Cancer of the Lung. 2014 Edition. Available at: https://www.cancer.ie/sites/default/files/content-attachments/cancer_of_the_lung_2016_web.pdf. Accessed: 2 May 2019.