About Lung Cancer

About Lung Cancer

Understand the basics of lung cancer, diagnosis and different treatment options

ALK Mutation in Lung Cancer

About 5% of NSCLCs have a rearrangement in a gene called anaplastic lymphoma kinase (ALK).4  This change is most often seen in non-smokers (or light smokers) who have the adenocarcinoma subtype of NSCLC.4  The ALK gene rearrangement produces an abnormal ALK protein that causes the cells to grow and spread.4 ALK mutation test can help find out if the tumour has developed the mutation.4 Nowadays, drugs that target the ALK mutation are available for first- and second-line treatment.4
 

 

 

 

4. ACS. Non-Small Cell Lung Cancer. Available at: https://www.cancer.org/content/dam/CRC/PDF/Public/8703.00.pdf. https://www.cancer.org/content/dam/CRC/PDF/Public/8705.00.pdf. https://www.cancer.org/content/dam/CRC/PDF/Public/8706.00.pdf. Accessed: 2 May 2019.